Sarcoidosis, A Case report and review of the literature.
Aust Dent J 59: 389-394 5
Khammissa R, Jadwat Y, Lemmer J, Feller L 2014.
Sarcoidosis is a chronic multi-system immuno-inflammatory disorder
characterized by non-caseating granulomatous infiltration of affected tissues that
may result in fibrosis and organ dysfunction. It generally affects genetically
predisposed young adults who develop a local dysregulated cell-mediated
immune response towards an undefined 'sarcoidal antigen'. From recent data, it
has become evident that Propionibacterium acnes and Mycobacterium
tuberculosis are the probable antigenic agents which initiate sarcoidosis. Oral
sarcoidosis is rare with only about 70 cases having been reported in the
literature. The purpose of this report is to present a case of oral and cutaneous
sarcoidosis in a black female that was probably triggered by mycobacteria.