Sarcoidosis, A Case report and review of the literature.

Aust Dent J 59: 389-394 5

Khammissa R, Jadwat Y, Lemmer J, Feller L 2014.

Sarcoidosis is a chronic multi-system immuno-inflammatory disorder

characterized by non-caseating granulomatous infiltration of affected tissues that

may result in fibrosis and organ dysfunction. It generally affects genetically

predisposed young adults who develop a local dysregulated cell-mediated

immune response towards an undefined 'sarcoidal antigen'. From recent data, it

has become evident that Propionibacterium acnes and Mycobacterium

tuberculosis are the probable antigenic agents which initiate sarcoidosis. Oral

sarcoidosis is rare with only about 70 cases having been reported in the

literature. The purpose of this report is to present a case of oral and cutaneous

sarcoidosis in a black female that was probably triggered by mycobacteria.