Sunlight (actinic) keratosis: an update.Feller L, Khammissa RA, Wood NH, Jadwat Y, Meyerov R, Lemmer J.
Department of Periodontology and Oral Medicine, School of Dentistry, Faculty of Health Sciences, University of Limpopo, Medunsa Campus, South Africa.
Plasma cell gingivitis: does it exist? Report of a case and review of the literature.Jadwat Y, Meyerov R, Lemmer J, Raubenheimer EJ, Feller L.
Department of Periodontology and Oral Medicine, School of Dentistry, University of Limpopo, Medunsa Campus, South Africa.
Plasma cell gingivitis is an uncommon inflammatory condition of uncertain aetiology. It is characterized clinically by enlarged erythemathous gingivae, a velvety texture and histopathologically by a dense plasmacytic infiltrate in the lamina propria. We present a case of a 19-year-old female who had what appeared to be plasma cell gingivitis. The clinical and histopathological differential diagnosis of plasma cell gingivitis is discussed and an argument is presented raising certain doubts whether plasma cell gingivitis is a distinct clinicopathological entity or not.
PMID: 19054906 [PubMed - indexed for MEDLINE]
Localized aggressive periodontitis associated with unusual gingival enlargement posing a diagnostic dilemma: a case report.2008 May;63(4):230-2.
Jadwat Y, Anagnostopoulos C, Wood NH, Lemmer J, Meyerov RH, Feller L.
Department of Periodontology and Oral Medicine. School of Dentistry, University of Limpopo, Medunsa Campus, South Africa.
This is a case report of localized aggressive periodontitis associated with unusual gingival enlargement. There was difficulty both clinically and histologically in deciding whether the gingival enlargement was a pyogenic granuloma or a Kaposi sarcoma. The diagnosis of Kaposi sarcoma was eventually ruled out by the failure of immunohistopathological examination to demonstrate the presence of HHV-8 DNA markers, and by the clinical response of the lesions to antimicrobial agents. Once a definitive diagnosis was made, the patient was treated conventionally.
PMID: 18689337 [PubMed - indexed for MEDLINE]
Human immunodeficiency virus (HIV)-associated extranodal T cell non-Hodgkin lymphoma of the oral cavity.2008 Apr;63(3):158-61.
Wood NH, Feller L, Raubenheimer EJ, Jadwat Y, Meyerov R, Lemmer J.
Department of Periodontology and Oral Medicine, School of Dentistry, University of Limpopo, Medunsa Campus.
T cell non-Hodgkin lymphoma is characterized by uncontrolled cellular proliferation of immature malignant clones. HIV-associated T cell non-Hodgkin lymphoma comprises a heterogeneous group of lymphoproliferative neoplastic entities classified according to morphological, immunological, genetic and clinical features. Extranodal T cell non-Hodgkin lymphoma of the oral cavity is uncommon. A case is presented with extranodal T cell non-Hodgkin lymphoma as an initial sign of HIV-infection. The characteristics of HIV-associated non-Hodgkin lymphoma are discussed.
PMID: 18689348 [PubMed - indexed for MEDLINE]
Compliance levels attained in managing supportive therapy over a five-year period in a periodontal private practice in Johannesburg, South Africa.Int Dent S A. 2008; 10(2):24-34
Jadwat Y, Buskin A, Feller L.
Objectives: The aim of this study was to investigate the level of compliance attained by patients who are involved in supportive periodontal therapy in a private periodontal practice in Johannesburg, South Africa. Materials and Method: This retrospective study encompassed a five year period of supportive periodontal therapy. A random selection of 304 clinical records of patients who had completed active periodontal treatment was used. Patients were grouped according to gender, age, socio-economic class, type of periodontal disease, the type of treatment rendered, and level of compliance attained. Compliance was classified into four categories based on attendance: complete compliance, partial compliance, erratic and noncompliance. Results: Only 20.72% of all patients belonging to our sample population achieved complete compliance. In the gender groups, 24.11% of male patients and 17.79% of female patients were in complete compliance. Older patients had a higher tendency to adhere to the supportive periodontal therapy programme compared to younger patients. In the socio-economic groups, skilled manual workers demonstrated the highest complete compliance rates (22.86%). When compliance was related to the type of periodontal disease it was found that individuals with chronic periodontitis had higher levels of complete compliance, than those suffering from aggressive periodontitis. Patients receiving plaque control instructions and scaling only, were the most compliant.
Conclusion: The results in this study are in agreement with similar studies and confirm a poor complete compliance with supportive periodontal therapy. When the various categories were assessed, individuals in the age category ≥ 61 years were significantly more compliant.
A report of oral extramedullary acute myeloid leukaemia (AML) in an 8-year-old girl with newly diagnosed AML-M4Eo.2007 Oct;62(9):390, 392-3.
Anagnostopoulos C, Jadwat Y, Wood NH, Meyerov R, Lemmer J, Bouckaert M, Feller L.
Department of Maxillofacial and Oral Surgery, School of Dentistry, University of Limpopo (Medunsa Campus), South Africa.
Acute myeloid leukaemia (AML), characterized by proliferation of immature neoplastic myeloid cells, is uncommon in childhood. We present a case of an 8-year-old girl with AML-M4Eo who had an extramedullary leukaemic tumour in the oral cavity.
PMID: 18260548 [PubMed - indexed for MEDLINE]
HIV-associated oral Kaposi sarcoma and HHV-8: a review.2007 Oct;9(4):129-36.
Feller L, Lemmer J, Wood NH, Jadwat Y, Raubenheimer EJ.
Department of Periodontology and Oral Medicine, Faculty of Dentistry, University of Limpopo (Medunsa Campus), South Africa.
Kaposi sarcoma is the most common malignant tumour associated with HIV infection. In the majority of cases oral tissues are involved and in 22% the initial presentation is in the oral cavity. The oral lesions are either single or multifocal, and the palate, gingiva and tongue are the sites most frequently involved. The pathogenesis of Kaposi sarcoma in HIV-seropositive subjects is complex. It involves interaction between human herpesvirus-8 (HHV-8) and HIV, altered cellular signal transduction pathways, and increased production of cytokines and growth factors. The multifactorial nature and clinical stages in the growth of oral Kaposi sarcoma are discussed.
PMID: 17987883 [PubMed - indexed for MEDLINE]
Enamel dysplasia with odontogenic fibroma-like hamartomas: review of the literature and report of a case.2006 May;101(5):620-4. Epub
Feller L, Jadwat Y, Bouckaert M, Buskin A, Raubenheimer EJ.
Department of Periodontology and Oral Medicine, Medunsa Oral Health Centre, Faculty Of Dentistry, University Of Limpopo, South Africa.
This article reports on a case presenting with a rare syndrome characterized by enamel dysplasia and multiple unerupted teeth with large solid fibrous pericoronal lesions manifesting with odontogenic fibroma-like features. Our case shows in addition to these findings an anterior open bite malocclusion and gingival overgrowths. These overgrowths exhibit the microscopic features of the multiple pericoronal odontogenic fibroma-like lesions that appear to be the hallmark of this syndrome. This unusual case brings the total number documented in the literature to 5, all of which were reported from South Africa.
PMID: 16632274 [PubMed - indexed for MEDLINE]
Herpes zoster post-herpetic neuralgia.2005 Nov;60(10):432, 436-7.
Feller L, Jadwat Y, Bouckaert M.
Department of Periodontology and Oral Medicine, Medunsa Oral Health Centre, Faculty of Dentistry, University of Limpopo, Medunsa Campus.
Post-herpetic neuralgia (PHN) is the most frequent complication of herpes zoster and often results in significant morbidity and a reduction in the patient's quality of life. The peripheral nerve injury that occurs during the acute phase of herpes zoster (HZ) leads to an abnormal tonic impulse discharge from primary nociceptive afferent neurons which induce slow temporal summation. This "wind-up" phenomenon is responsible for continuous partial depolarisation of second-order neurons with increased spontaneous impulse discharge and expanded receptive fields within the dorsal horn nociceptive neurons. The abnormal central processing involves the activation of N-methyl-D-aspartate (NMDA) receptors resulting in neuropathic pain, characterized by spontaneous pain, hyperalgesia and allodynia which is typical of PHN. In addition, tonic input from non-nociceptive AB afferent neurons, maintained by sympathetic efferent activity, contribute to the development and maintenance of neuropathic pain in general, and a burning sensation in particular.
Herpes zoster: a review of the literature and report of a case.SADJ. 2005 Oct;60(9):380-2, 384.
Feller L, Jadwat Y.
Department of Periodontology and Oral Medicine, Medunsa Oral Health Centre, Faculty of Dentistry, Medunsa Campus, University of Limpopo.
PMID: 16320529 [PubMed - indexed for MEDLINE]
Kaposi sarcoma and calcium channel blocker-induced gingival enlargement occurring simultaneously: review of the literature and report of a case.Oral Biosci Med 2004; 4:1-7.
Feller L, Jadwat Y, Raubenheimer EJ.
Summary: The gingiva is a site which hosts a great number of overgrowths; plaque induced and drug induced gingival enlargements, neoplastic lesions and gingival reactive overgrowths with or without calcification. Key words: Kaposi sarcoma, gingival overgrowth, calcium channel blocker.
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